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October 16, 2018

Resistance to HIV medications rare during preexposure prophylaxis

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Primary drug resistance to either tenofovir disoproxil fumarate (TDF) and/or emtricitabine (FTC, Truvada—Gilead) was rare in people who acquired HIV infection while enrolled in a preexposure...
July 16, 2018

Drug interactions are common among older adults receiving antiretroviral therapies

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A cross-sectional observational study published in the Journal of Acquired Immune Deficiency Syndromes involving 744 patients with HIV receiving antiretroviral treatment and at least one...
April 2, 2018

Two-drug regimens might be as effective as three-drug regimens for HIV-1 infections

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The fixed-dose combination regimen of dolutegravir/rilpivirine (Juluca—ViiV Healthcare) administered as one tablet daily was found to be noninferior to traditional three-drug antiviral regimens...
September 25, 2017

Strategies for conception in HIV-discordant couples

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A new report from CDC outlines strategies for HIV-discordant couples (i.e., uninfected female, infected male) who wish to conceive. Strategies include intercourse without a condom around the time...
July 24, 2017

Opioid pharmacokinetic drug interactions common, but manageable

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Data from more than 50 randomized controlled trials (RCTs) showed that opioid analgesic–related pharmacokinetic (PK) drug–drug interactions with various agents including antiplatelet agents,...

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APhA DrugInfoLine (ISSN 2162-3015) is a weekly publication of, and is owned and copyrighted by the American Pharmacists Association, the national professional society of pharmacists. Materials in APhA DrugInfoLine do not neccessarily represent the policy, recommendations, or endorsement of APhA. The publisher, authors, editors, reviewers, and contributors have taken care to ensure that the information contained in APhA DrugInfoLine is accurate and current; however, they shall have no ability to any person or entity with regard to claims, losses, or damage caused or alleged to be caused, directly or indirectly by use of any information contained in the publication. All decisions about drug therapy must be based on independent judgement of the clinician.