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Some diabetic neuropathy medications are associated with falls in older adults

KEY POINT

Use of tricyclic antidepressants (TCAs) or gabapentinoids increased the risk of falls and fractures in older adults with diabetic peripheral neuropathy (DPN), according to results of an observational study published in the Journal of the American Geriatrics Society.

SOURCES

Randolph AC, et al. Tricyclic antidepressant and/or γ‚Äźaminobutyric acid–analog use is associated with fall risk in diabetic peripheral neuropathy. J Am Geriatr Soc. 2019;67(6):1174–81.

American Diabetes Association. Microvascular complications and foot care: Standards of medical care in diabetes–2019. Diabetes Care. 2019;42(Suppl 1):S124–S138.

American Geriatrics Society Beers Criteria Update Expert Panel. American Geriatrics Society 2019 updated AGS Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc. 2019;67(4):674–94.