Alternative Medicines Corner

Back to articles

Garlic Supplements Interact with Antiretroviral Medication

KEY POINT

Garlic supplements, acting through an asyet unidentified mechanism, decrease serum concentrations of saquinavir (Fortovase—Roche). The drop in blood levels is sufficient to cause treatment failures.

SOURCES

Piscitelli SC et al. The effect of garlic supplements on the pharmacokinetics of saquinavir. Clin Infect Dis. 2002;34:234–8.