Alternative Medicines Corner

Back to articles

Herbal Interactions: Concern Grows


From the medical literature to television news programs, big concerns have arisen about interactions between traditional medications and herbal drugs. In particular, new information last month about St. John’s wort prompted an FDA advisory for prescribers, pharmacists, and patients (


Piscatelli SC et al. Indinavir concentrations and St. John’s wort. Lancet. 2000;355:547.

Ruschitzka F et al. Acute heart transplant rejection due to St. John’s wort. Lancet. 2000;355:548.

Various authors. Safety of St. John’s wort (Hypericum perforatum). Lancet. 2000;355:575 ff.