Alternative Medicines Corner

Back to articles

Ipriflavone, Garlic Studies Show Need for Evidence-Based Approach

KEY POINT

In a well-designed study, ipriflavone failed to prevent bone loss but produced lymphocytopenia among women at risk for osteoporosis. A review of published trials of garlic show that the agent has some small beneficial effects on lipid and antiplatelet factors, insignificant effects on blood pressure, and no effect on glucose.

SOURCES

Alexandersen P et al. Ipriflavone in the treatment of postmenopausal osteoporosis: a randomized controlled trial. JAMA. 2001;285:1482–8.

Ackermann RT et al. Garlic shows promise for improving some cardiovascular risk factors. Arch Intern Med. 2001;161:813–24.