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Ipriflavone, Garlic Studies Show Need for Evidence-Based Approach


In a well-designed study, ipriflavone failed to prevent bone loss but produced lymphocytopenia among women at risk for osteoporosis. A review of published trials of garlic show that the agent has some small beneficial effects on lipid and antiplatelet factors, insignificant effects on blood pressure, and no effect on glucose.


Alexandersen P et al. Ipriflavone in the treatment of postmenopausal osteoporosis: a randomized controlled trial. JAMA. 2001;285:1482–8.

Ackermann RT et al. Garlic shows promise for improving some cardiovascular risk factors. Arch Intern Med. 2001;161:813–24.