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Quality of Dietary Supplements: A Long-term Challenge


Tests of St. John’s wort products from the Frankfurt, Germany, area show unacceptable variation in the ingredients believed to exert antidepressant effects. Since Germany is widely recognized as having the best regulated system for dietary supplements, the findings highlight the challenges facing the herbal products industry, FDA, health professionals, and patients.


Wurglics M et al. Comparison of German St. John’s wort products according to hyperforin and total hypericin content. J Am Pharm Assoc. 2001;41:560–6.

Kingston R, Chaffin J. On the advent of FDA’s promulgation of GMPs: challenges remain for the natural pharmacist practitioner. Natural Pharm. Submitted for publication.