Alternative Medicines Corner

Back to articles

Supplementation or Screening?


Screening for elevated total plasma homocyst( e)ine (tHcy) levels—and treatment of patients with high concentrations—is more cost-effective than universal daily supplementation with folic acid and vitamin B12, according to an analysis of clinical and economic implications of recent research.


Nallamothu BK et al. Potential clinical and economic effects of homocyst(e)ine lowering. Arch Intern Med. 2000;160:3406–12.