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Safety concerns with digoxin use


Use of digoxin in patients with atrial fibrillation (AF) was associated with an increased risk of death, specifically when serum concentrations were 1.2 ng/mL or higher or when treatment was newly initiated, according to results of a new analysis published in the Journal of the American College of Cardiology.


Lopes RD, et al. Digoxin and mortality in patients with atrial fibrillation. J Am Coll Cardiol. 2018;71(10):1063–74.        

Turakhia MP, et al. Digoxin in atrial fibrillation: Leave it out of the medicine cabinet. J Am Coll Cardiol. 2018;71(10):1075–7.