Endocrinology

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Transdermal Testosterone Treatment: Tolerated in Women with Premature Ovarian Failure

KEY POINT

Transdermal testosterone patches have produced increased androgen levels and have been tolerated well in women with premature ovarian failure (POF). These women have lower serum androgen levels than those who menstruate regularly, and estrogen supplementation has not protected against bone loss in some patients. Researchers are testing whether testosterone supplementation can protect these patients from osteopenia and osteoporosis.

SOURCES

Kalantaridou SN et al. Transdermal testosterone replacement for young women with spontaneous premature ovarian failure: a pilot study. Paper presented at 82nd Annual Meeting of Endocrine Society, June 22, 2000, Toronto, Ontario, Canada.