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Live vaccine linked to beneficial, nonspecific effects against infections

KEY POINT

Data from a large cohort of Danish children showed that receipt of live MMR (measles, mumps, and rubella) vaccine after administration of two or three doses of inactivated DTaP–IPV–Hib (diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae type b) was associated with a lower rate of hospital admissions for any infection compared with DTaP–IPV–Hib being the most recently administered vaccine.

SOURCES

Sorup S et al. Live vaccine against measles, mumps, and rubella, and the risk of hospital adminssions for nontargeted infections. JAMA. 2014;311(8):826–835.  

Goldblatt D, Miller E. Nonspecific effects of vaccines [editorial]. JAMA. 2014;311(8):804–805.