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Varicella vaccine protection persists in largest, longest study of effectiveness to date

KEY POINT

In children who received the varicella virus vaccine (Varivax—Merck), the average incidence of varicella infection at 14 years post-vaccination was 9- to 10-fold times lower than historic prevaccine incidence. Most breakthrough varicella cases were mild (50 or less lesions) and occurred soon after vaccination, with no breakthrough cases reported after a second vaccine dose.

SOURCES

Baxter R et al. Long-term effectiveness of varicella vaccine: a 14-year, prospective cohort study. Pediatrics. 2013;[Epub ahead of print].