Focus on Lipids Care

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Harmful effects of torcetrapib examined


Harmful effects of torcetrapib are attributed to mineralocorticoid excess and nonfunctional, potentially proatherogenic HDL particles.


Barter PJ et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med. 2007;357:2109–22. 

Rader DJ. Illuminating HDL—is it sill a viable therapeutic target? N Engl J Med. 2007;357:2180–3.