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High-dose statins for metabolic syndrome

KEY POINT

Confirming the possibility that statins could be effective in reducing the cardiovascular risks associated with metabolic syndrome, two recently published studies support use of high-dose atorvastatin (Lipitor—Pfizer) for reducing cardiovascular and stroke risk. These trials, in addition to several other studies over the past 12 years, support the premise that when it comes to cholesterol, specifically LDL, “lower is better.”