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April 28, 2015

Coenzyme Q10 for statin-induced myopathy

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In a meta-analysis of statin-related myopathy trials, supplementation with coenzyme Q10 did not decrease muscle pain or significantly change plasma creatinine kinase (CK) activity, compared with...
April 28, 2015

Most coronary risk calculators overestimate risk

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Four out of five cardiovascular (CV) risk calculators, including the most recent one released by the American Heart Association/American College of Cardiology (AHA–ACC) in 2013, considerably...
April 7, 2015

Statins and clarithromycin: Role of non-CYP3A4 interactions

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Results of a large population-based cohort study suggest that there may be a drug–drug interaction between clarithromycin, a potent cytochrome P450 3A4 (CYP3A4) inhibitor, and statins not...
March 24, 2015

Genetic variants may explain increased diabetes risk with statins

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Genetic variants near the gene that encodes the HMG-coenzyme A (HMG-CoA) reductase protein may explain the association between statin use and an increased risk of type 2 diabetes, according to a...
February 17, 2015

High-intensity statins underused after heart hospitalization

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Approximately three-quarters of Medicare beneficiaries failed to fill a prescription for a high-intensity statin within 90 days of hospital discharge for a coronary heart disease (CHD) event,...

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APhA DrugInfoLine (ISSN 2162-3015) is a weekly publication of, and is owned and copyrighted by the American Pharmacists Association, the national professional society of pharmacists. Materials in APhA DrugInfoLine do not neccessarily represent the policy, recommendations, or endorsement of APhA. The publisher, authors, editors, reviewers, and contributors have taken care to ensure that the information contained in APhA DrugInfoLine is accurate and current; however, they shall have no ability to any person or entity with regard to claims, losses, or damage caused or alleged to be caused, directly or indirectly by use of any information contained in the publication. All decisions about drug therapy must be based on independent judgement of the clinician.