Nephrology

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Lower uric acid levels may be better in chronic kidney disease

KEY POINT

Use of febuxostat (Uloric—Takeda) 40 mg once daily for 6 months in patients with asymptomatic hyperuricemia and stage 3 or 4 chronic kidney disease (CKD) slowed the decline in estimated glomerular filtration rate (eGFR) compared with placebo, according to results of a small, single-center study published in the American Journal of Kidney Diseases.