Psychiatry

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Cholinesterase Inhibitors Provide Modest Benefits in Alzheimer’s Disease

KEY POINT

Cholinesterase inhibitors, the primary treatment for patients with Alzheimer’s disease, provide real but only modest benefits, according to a recently published meta-analysis of 29 studies.

SOURCES

Trinh N et al. Efficacy of cholinesterase inhibitors in the treatment of neuropsychiatric symptoms and functional impairment in Alzheimer disease: a meta-analysis. JAMA. 2003;289:210–6.