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Long-term oxygen use not beneficial in some patients with COPD


Use of long-term supplemental oxygen therapy in patients with chronic obstructive pulmonary disease (COPD) who had blood oxygen saturation levels between 89% and 93% at rest or less than 90% during exertion did not result in improved outcomes or prolong life, according to results of the Long-Term Oxygen Treatment Trial (LOTT) published in the New England Journal of Medicine.


The Long-Term Oxygen Treatment Trial Research Group. A randomized trial of long-term oxygen for COPD with moderate desaturation. N Engl J Med. 2016;375(17):1617–27.

Ekström, M. Clinical usefulness of long-term oxygen therapy in adults. N Engl J Med. 2016;375(17):1683–4